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September 10, 2025Journal of Pediatric SurgeryOpen Access

Surgical Management of Paediatric Appendiceal Neuroendocrine Tumors: A 26-year Danish Nationwide retrospective cohort study

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Authors

SJS. JensenOdense University HospitalSGSara GiovannoniOdense University HospitalMAMona P. AnkerstjerneOdense University Hospital

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Overview

Retrospective cohort study identifies key characteristics and surgical outcomes of appendiceal neuroendocrine tumors, suggesting a need for specific pediatric guidelines.

Key Points

  • The study found an annual incidence of appendiceal neuroendocrine tumors of 6.37 per million children, indicating their rarity in the pediatric population.
  • In total, 21.5% of children required secondary surgeries due to histopathological risk factors, although no residual tumors were identified.
  • The research highlights the need for specific pediatric surgical guidelines, as histopathological risk factors did not show significant prognostic value.
  • The lack of recurrence and aNET-related mortality supports the notion that these tumors generally carry an excellent prognosis.

Cite This Study

Jensen et al. (2025) studied this question.

synapsesocial.com/papers/68c19f9154b1d3bfb60daf44https://doi.org/10.1016/j.jpedsurg.2025.162506
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