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Triglyceride glucose-waist height ratio index is a promising and robust glucose and lipid metabolism indicator for predicting long-term type 2 diabetes: insights from a Japanese prospective cohort data from 12 years

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TyG-WHtR is identified as a robust predictor for long-term type 2 diabetes risk, facilitating early detection.
The study's ROC analysis shows TyG-WHtR has an area under the curve value of 0.786, outperforming other indicators.
Subgroup analyses confirmed TyG-WHtR's predictive capability over a 12-year follow-up across different populations.
With a hazard ratio of 2.99, TyG-WHtR offers personalized risk stratification for individuals at high risk for T2D.

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Prospective cohort analysis evaluated 16 indicators for type 2 diabetes risk, revealing TyG-WHtR's strong predictive value.

Dou et al. (2025) studied this question.

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