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This review demonstrates the potential of CRISPR technology to enhance biopesticides' efficacy in pest resistance, suggesting new avenues for sustainable agriculture.
Clustered regularly interspaced short palindromic repeats (CRISPR) technology has revolutionized genetic engineering, opening unprecedented opportunities for biopesticide development. By enabling precise genetic modifications, CRISPR is addressing the challenges of pest resistance, environmental safety, and specificity in biopesticide applications. This review explores innovations in CRISPR-driven biopesticide development, assesses their socioeconomic and ecological impacts, and identifies future directions for research and application. The integration of CRISPR with digital technologies, regulatory hurdles, and strategies for sustainable pest management are also discussed. By outlining the route of CRISPR from controlled laboratory surroundings to real-world field applications, this review underlines its evolutionary perspective in transforming pest control prototypes. The conjunction of gene-editing knowledge, agroecological responsibility, and agronomic invention marks an innovative period in which CRISPR-driven biopesticides can play a fundamental role in safeguarding agricultural sustainability as well as climate resilience..
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Mishra et al. (2025) studied this question.
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