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September 10, 2025Blood Cancer JournalOpen Access

A clinico-genomic prognostic model for primary myelodysplastic neoplasm in Asia

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Authors

HGHarinder GillRYRita YimPLPaul Lee

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Overview

This model predicts overall and leukemia-free survival in Asian patients with primary myelodysplastic neoplasm, suggesting improved outcomes.

Key Points

  • The Asian Prognostic Scoring System improves overall survival prediction in patients with primary myelodysplastic neoplasm.
  • Key genomic factors like monosomy 7 and TP53 mutations were linked to poorer outcomes, influencing patient stratification.
  • The prognostic scores were developed from a large cohort of 1225 patients, emphasizing the relevance of genetic analysis.
  • The APSS outperformed the International Prognostic Scoring System in predicting survival metrics for this population.

Cite This Study

Gill et al. (2025) studied this question.

synapsesocial.com/papers/68c1a40f54b1d3bfb60deceehttps://doi.org/10.1038/s41408-025-01339-0
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