Localized Cutaneous Nodule in an Elderly Patient

Localized cutaneous nodules are common in the elderly and may indicate benign or malignant conditions. This case highlights the diagnostic challenge of cutaneous leishmaniasis (CL), which mimicked malignancy in an elderly woman with minimal travel history. CL due to L. donovani is rare in Europe and was confirmed via histopathology and staining. Given the patient’s renal comorbidities and prior cancer, local treatment was preferred over systemic therapy. CL should be included in the differential diagnosis of chronic nodules, especially in patients with past travel to endemic areas. Biopsy remains crucial for accurate diagnosis and appropriate, individualized management.