Observational analysis reveals T H 17 cells regulate chemokine expression in epithelial tissues, suggesting new targets for colitis and cancer therapies.
Key Points
T H 17 cytokines dictate the sensitivity of mice to DSS-induced colitis and cancer, indicating potential therapeutic pathways.
C/EBPβ ablation in cancer cells enhances chemokine expression, promoting sensitivity to anti–PD-1 immunotherapy.