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Visible-Light-Driven Trifluoroacetylation of Azauracils

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This novel method provides an eco-friendly trifluoroacetylation for bioactive molecules, indicating strong functional group tolerance.

The method significantly enhances the accessibility of trifluoroacetylated compounds for various applications.
Using visible light as a catalyst allows for an efficient and simplified synthetic process without expensive additives.
It shows excellent tolerance to different functional groups, making it versatile for late-stage modifications.
By employing oxygen as the oxidant, the approach adheres to sustainable chemistry practices.

An et al. (2025) studied this question.

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