Observational analysis shows no survival benefit from R0 resection in laryngeal chondrosarcoma, suggesting that laryngeal function preservation should be prioritized.
Survival outcomes after resection of laryngeal chondrosarcoma are generally excellent, and contemporary management should aim to optimize laryngeal function and tailor the surgical approach based on subsite (accessibility of resection), initial extent of disease (when and how much to resect), and histologic grade. R0 resection does not appear to improve overall survival and should not usually be prioritized over preserving laryngeal function, especially in cases with a less aggressive oncologic profile.
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Kattar et al. (2025) studied this question.
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