Current approaches to the treatment of ovarian cancer with peritoneal dissemination

The diversity of current treatment methods of ovarian cancer (OC) with peritoneal dissemination, such as cytoreductive surgery (CRS), hyperthermic intraperitoneal chemotherapy (HIPEC), and pressurized intraperitoneal aerosol chemotherapy (PIPAC), complicates the selection of an optimal strategy and may delay the initiation of treatment. This review systematizes current treatment approaches and presents practical recommendations based on an analysis of recent scientific data. A systemic literature search was conducted in MEDLINE, PubMed, and eLibrary for the period from 2015 to 2025 using the keywords like “ovarian cancer,” “peritoneal dissemination,” “cytoreductive surgery,” “HIPEC,” and “PIPAC.” Studies unrelated to the topic were excluded. The review includes primary studies focused on the treatment of ovarian cancer with peritoneal dissemination.