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This investigation demonstrates the anti-inflammatory effects of barringtonia asiatica in albino mice, suggesting its potential as a safe therapeutic option.
The leaves of Barringtonia asiatica (Lecythidaceae) have long been employed in traditional medicine for their therapeutic benefits, including anti-inflammatory properties. This study evaluated the anti-inflammatory effects of ethanolic leaf extracts of B. asiatica in vivo using carrageenan-induced paw edema in Swiss albino mice. Mice were administered extract concentrations of 25%, 50%, and 75%, while diclofenac sodium served as a positive control. Phytochemical analysis revealed the presence of flavonoids, saponins, and other bioactive constituents. The 75% extract demonstrated significant anti-inflammatory effects, comparable to diclofenac. Acute oral toxicity testing confirmed the extract's safety. These findings support the traditional medicinal use of B. asiatica and its potential as a safe, plant-based anti-inflammatory agent.
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Casiple et al. (2025) studied this question.
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