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September 10, 2025BMJ Surgery Interventions & Health TechnologiesOpen Access

Long-term outcomes of initial thoracic endovascular repair versus medical therapy in acute uncomplicated type B aortic dissection: real-world evidence from a nationwide claims database in Japan – a retrospective cohort study

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Authors

YKYuki KimuraHOHiroshi OhtsuNYNaohiro Yonemoto

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Overview

Retrospective cohort study compares outcomes of TEVAR and medical therapy in acute aortic dissection, indicating no survival benefit.

Key Points

  • No significant differences in aorta-related events or all-cause mortality between TEVAR and medical therapy groups.
  • At 60 months, aorta-related event rates were 21.9% for TEVAR and 19.9% for medical therapy, with p=0.99.
  • Using propensity score matching, 96 TEVAR and 480 medical therapy cases were analyzed from a nationwide claims database.
  • Findings suggest no immediate survival benefit from TEVAR, calling for further randomized controlled trials.

Cite This Study

Kimura et al. (2025) studied this question.

synapsesocial.com/papers/68c1b18554b1d3bfb60e84bahttps://doi.org/10.1136/bmjsit-2024-000361
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