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September 10, 2025

Five cases of short stature and delayed puberty with primary empty sella syndrome

Key Points

All five boys presented with short stature and delayed puberty, indicating hormonal evaluation is necessary.
Pituitary MRI revealed empty sella in all cases, leading to a diagnosis of panhypopituitarism.
No prior risk factors for growth hormone deficiency were identified in these patients.
Active monitoring of hormonal status in children is crucial for managing primary empty sella syndrome.

Abstract

We reported five adolescent boys of proportionate short stature and delayed puberty. None of the patients had any risk factors or stigma of growth hormone and other pituitary hormone deficiency. But investigations revealed panhypopituitarism with empty sella detected by pituitary MRI in all cases. Children with primary empty sella syndrome require an active evaluation of hormonal status for long-term outcomes. J Assoc Clin Endocrinol Diabetol Bangladesh, July 2022; 1 (2): 69-71

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Cite This Study

Rahman et al. (Mon,) studied this question.

synapsesocial.com/papers/68c1b1a154b1d3bfb60e9264 https://doi.org/https://doi.org/10.3329/jacedb.v1i2.78423

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