Case report reveals effective surgical management of solitary pulmonary metastasis, suggesting the role of minimally invasive techniques.
Endometrial adenocarcinoma frequently metastasizes to distant organs, with the lungs being a common site. Pulmonary metastases typically present as multiple nodules. However, solitary lesions are uncommon and may offer surgical opportunities. This case report describes a 42-year-old woman with a history of stage IV endometrial adenocarcinoma who was found to have a solitary hypermetabolic pulmonary nodule on surveillance by Positron Emission Tomography/Computed Tomography (PET-CT). She underwent a uniportal video-assisted thoracoscopic surgery (VATS) anatomical segmentectomy of the left lingular segments (S4-S5). Histopathology confirmed moderately differentiated metastatic adenocarcinoma of endometrial origin with clear surgical margins. This case highlights the feasibility and oncologic effectiveness of uniportal VATS segmentectomy in managing isolated pulmonary metastases from gynecologic malignancies, emphasizing the role of minimally invasive surgery in selected patients.
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Carrillo et al. (2025) studied this question.
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