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September 10, 2025Journal of the National Comprehensive Cancer Network58 citations

NCCN Guidelines® Insights: Uterine Neoplasms, Version 3.2025

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NANadeem R. Abu‐RustumSCSusana M. CamposSASudha Amarnath

Key Points

  • The guidelines provide updated recommendations for managing endometrial cancer and uterine sarcoma, enhancing patient care.
  • Key revisions include updates on the FIGO staging system and new systemic therapy options for endometrial cancer treatment.
  • The NCCN Cervical Uterine Panel regularly reviews new data and feedback, ensuring guidelines reflect current research and FDA approvals.
  • These insights focus on the recommendations for diagnostic workup, clinical staging, and various treatment options available for patients.

Abstract

The NCCN Guidelines for Uterine Neoplasms provide recommendations for diagnostic workup, clinical staging, and treatment options for patients with endometrial cancer and uterine sarcoma. The NCCN Cervical Uterine Panel meets at least annually to review comments from reviewers within their institutions; examine relevant new data from publications, abstracts, and recent FDA approvals; and reevaluate and update recommendations. These NCCN Guidelines Insights summarize the panel’s deliberations on the new FIGO 2023 staging system and updates on the new systemic therapy recommendations for the management of endometrial cancer.

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Abu‐Rustum et al. (2025) studied this question.

synapsesocial.com/papers/68c1b35454b1d3bfb60e9db4https://doi.org/10.6004/jnccn.2025.0038
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