Comparison of the Corneal High-Order Aberration and Relative Corneal Refractive Power Distribution Induced by Different Orthokeratology Lenses Designs

Purpose: This study compared the myopia control effects of corneal high-order aberrations (CHOA) from two orthokeratology (OK) lenses based on their relative corneal refractive power shifts. Methods: In this prospective cohort study, 101 school children with low to moderate myopia were divided into three groups: group A (N=35) used 3-curve design lenses, group B (N=31) used 4-curve design lenses, and group C (N=35) wore regular spectacles. Cycloplegic refraction, visual acuity, and axial length (AL) were measured at baseline and after one year. Keratometry and CHOA were assessed before and after 3 months of lens wear. Relative corneal refractive power shifts and summed corneal power change (SCPC) were calculated. One-way ANOVA and planned comparison analyzed group differences. Results: Group B showed significantly slower AL elongation than group A ( P =0.017) after OK treatment. Group B's SCPC was significantly higher than group A's ( P ≤0.005). Group B had a significant increase in horizontal coma ( P =0.004). Increased SCPC led to more coma aberration with four-curve lens wear ( P <0.01). Conclusions: The four-curve lens design was more effective in slowing AL elongation for OK treatment. It also caused significantly higher horizontal coma aberration than the three-curve design.