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September 10, 2025MetabolitesOpen Access

Ketogenic Metabolism in Neurodegenerative Diseases: Mechanisms of Action and Therapeutic Potential

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Authors

MPMarta PawłowskaJKJoanna KruszkaMPMarta Porzych

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Overview

This review highlights ketogenic metabolism's role in reducing oxidative stress and neuroinflammation in neurodegenerative diseases.

Key Points

  • Ketogenic metabolism shows potential therapeutic benefits in neurodegenerative diseases, suggesting it may help protect neurons.
  • Research indicates that ketone bodies can improve mitochondrial function and reduce oxidative stress in patients with neurodegenerative diseases.
  • This review provides an analysis of both dietary ketogenic interventions and exogenous ketone supplementation in treating neurodegenerative disorders.
  • The findings underscore the need for personalized approaches in applying ketogenic therapies due to patient-specific metabolic profiles.

Cite This Study

Pawłowska et al. (2025) studied this question.

synapsesocial.com/papers/68c1b61454b1d3bfb60eb82bhttps://doi.org/10.3390/metabo15080508
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