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Observational analysis found varied clinical recommendations for NEC management from AI systems, highlighting alignment challenges with European neonatal care standards.
Necrotizing enterocolitis (NEC) is a life-threatening emergency in neonatal medicine, especially among premature infants, with high morbidity and mortality. Despite the availability of evidence-based resources such as the European Standards of Care for Newborn Health, variations in clinical practice persist. Artificial intelligence (AI) systems based on large language models have recently gained attention as tools to support clinical decision-making. This study aimed to evaluate the alignment of two widely used AI applications-Chat Generative Pre-trained Transformer (ChatGPT) version 4.0 and Gemini-with the European neonatal care standards in providing clinical recommendations for the management of NEC.
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Uygun et al. (2025) studied this question.
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