Appendicitis Inflammatory Response Score in Comparison to Alvarado Score in Acute Appendicitis

Introduction: In resource-constrained environments like Pakistan, scoring systems are essential. When radiography is unavailable or ambiguous, these grading systems can be useful for clinical diagnosis, prompt transfer from primary care institutions, and surgical decision-making. The purpose of the current study was to validate the Alvarado-based appendicitis inflammatory response score in patients having appendicectomies for suspected acute appendicitis. Study design: Cross-sectional (validation) study. Settings: Department of Surgery, National Hospital, Lahore. Methodology: The study comprised 213 patients, aged 18 to 60 years presenting with suspected acute appendicitis undergoing appendectomy. Patients with known malignancies, pregnant women, and those with a sonographic diagnostic of an appendicular mass, abscess, or perforation were excluded. The AIR score was determined following a thorough history, examination, and basic laboratory testing. The Alvarado Score was used to make a clinical diagnosis of suspected cases of acute appendicitis. Results were compared with histopathology report. Results: 94.67% AIR score sensitivity, 79.37% specificity, 91.61% PPV, 86.21% NPV, and 90.14% diagnostic accuracy were used to diagnose acute appendicitis. 94.67% AIR score sensitivity, 79.37% specificity, 91.61% PPV, 86.21% NPV, and 90.14% diagnostic accuracy were used to diagnose acute appendicitis. Conclusion: For the precise diagnosis of acute appendicitis, the appendix inflammatory response score offers higher sensitivity and specificity.