Immunologic study estimates seroprevalence of IgG antibodies in RT-PCR negative individuals, suggesting important insights for infection control.
Background: Many studies examined the spread of SARS-CoV-2 within populations using seroprevalence. The aim of this study was to estimate the seroprevalence of SARS-CoV-2 specic IgG antibodies from May 2020 to December 2023 in Chandrapur, Maharashtra. Methods: The data was collected between May 2020 to Dec 2023. In this study, we conducted an immunologic study to determine the seroprevalence of anti-SARS-CoV-2 antibodies in hospitals. Blood samples were collected randomly from 390924 individuals who were SARS CoV-2 RT-PCR negative across Chandrapur, Maharashtra. The serum samples were tested for SARS-CoV-2 IgG antibodies using Enzyme linked Immunosorbent Assay (ELISA) method. Results: 14.32% of samples had anti-SARS-CoV 2 IgG antibodies, with a slightly higher incidence in males than in females. Additionally, people in the 21-40 age range and those living in cities showed higher levels of positivity. Conclusions: The signicance of anti-SARS-CoV-2 IgG antibody serosurveillance among RT-PCR negative persons is suggested by this study. This will assist in halting the spread of infection and developing infection prevention procedures.
No takes yet. Share an insight, caveat, or question.
Komatwar et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: