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September 10, 2025Journal of Controlled Release26 citationsOpen Access

Recent developments in the use of carbon-based nanomaterials in cancer therapy

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MAManuel AlgarraSVSara VinacuaAGAdrián Gil-Korilis

Key Points

  • Carbon-based nanomaterials show promise in transforming cancer therapy by offering unique properties.
  • The review categorizes nanomaterials, highlighting options like carbon quantum dots for cancer intervention.
  • Various therapies using carbon-based nanomaterials are examined, including targeted and photothermal approaches.
  • The findings indicate that carbon nanomaterials possess exceptional biocompatibility and optical properties.

Abstract

Cancer is one of the most complex health problems worldwide, demanding innovative approaches to achieve effective diagnosis, treatment and prevention. The field of nanomedicine, including nanomaterials and particularly carbon-based nanoparticles, have emerged as promising candidates to transform cancer therapy. This review presents a landscape of carbon nanomaterial- and nanoparticle-based cancer interventions. First, a brief overview of the categories of nanomaterials used is provided, including metal-based nanomaterials, mesoporous silicas, polymers and composites (most notably MXenes and metal-organic frameworks), proteins, and carbon-based nanomaterials, including carbon quantum dots. The latter has attracted significant attention due to their exceptional biocompatibility, tunable surface chemistry, and distinctive optical properties, making them ideal candidates for cancer diagnostic and therapeutic strategies. The second part of this review focuses on briefly presenting the various therapies developed with carbon-based nanomaterials based on chemo, radio, immuno, thargeted, hyperthermia, photodynamic, and photothermal therapies.

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Cite This Study

Algarra et al. (2025) studied this question.

synapsesocial.com/papers/68c1bb7854b1d3bfb60edd56https://doi.org/10.1016/j.jconrel.2025.114100
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