Case report highlights distinct components of serrated tubulovillous adenoma, suggesting links to colorectal carcinomas.
Serrated tubulovillous adenoma (STVA) is a rare type of colorectal polyp that exhibits characteristics of both serrated lesions and conventional adenomas. These polyps show frequent KRAS mutations and CpG island methylation. Therefore, they represent potential precursors to KRAS-mutated, microsatellite-stable colorectal carcinomas. We present a case clearly showing a demarcation line between the two distinct components of an STVA.
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Mitev et al. (2025) studied this question.
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