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January 1, 2025RSC MechanochemistryOpen Access

Correction: Mechanochemical kilogram-scale synthesis of rac-ibuprofen:nicotinamide co-crystals using a drum mill

Jan‐Hendrik Schöbel Frederik Winkelmann Joel Bicker Michael Felderhoff

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Key Points

This correction addresses a methodology refinement in the synthesis of co-crystals using a drum mill.
The mechanochemical process enables kilogram-scale production of ibuprofen and nicotinamide co-crystals efficiently.
Utilizing a drum mill improves the quality of the synthesized co-crystals significantly.
Enhanced mechanochemical synthesis may lead to improved pharmaceutical formulations in the industry.

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Implication

Correction notes the mechanochemical synthesis of co-crystals from ibuprofen and nicotinamide, indicating process improvements.

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Cite This Study

Schöbel et al. (2025) studied this question.

synapsesocial.com/papers/68c1bd4854b1d3bfb60eee67 https://doi.org/10.1039/d5mr90023a

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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