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This review examines adipocytokines' roles in weight management and metabolic health in postmenopausal women, suggesting potential interventions.
Obesity in postmenopausal women is a major global health concern due to hormonal and metabolic changes. This review explores the roles of ghrelin, leptin, adiponectin, insulin, AMPK, and vitamin D in energy regulation and weight fluctuation. Estrogen decline post-menopause alters metabolic balance, contributing to fat accumulation and insulin resistance. Reduced adiponectin and disrupted leptin–ghrelin signalling are linked with increased body mass index. Vitamin D sufficiency, alongside lifestyle changes, may support weight management in this population.
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Sukanya et al. (2025) studied this question.
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