Effects of Selenium and vitamin E against arsenic toxicity in Broiler

Currently arsenic contamination in Bangladesh is the world's biggest natural calamity in terms of total population affected in an area. Arsenic is spreading in various ways in the environment and significantly threatening the public health as well as the animal health of Bangladesh. Arsenic can enter the food chain, causing widespread distribution throughout the plant and animal kingdom. This work was done in broilers to study the comparative efficacy of Selenium and Vitamin E to prevent arsenic toxicity. Sixty broilers were used in this study, and broilers were divided into a control group (T₀), arsenic-treated group (T₁), Arsenic (As) plus Selenium treated group (T₂), and Arsenic (As) plus Vitamin E treated group (T₃). Each group consists of 15 broilers. Broilers of T₀ group were given normal feed and water and kept as control. Broilers of T₁, T₂, and T₃ were given 100 mg Arsenic (As) trioxide/kg body weight, mixed with drinking water daily for 35 days. In addition to arsenic (As) trioxide broilers of group T₂ and T₃ were fed with Selenium @ 0.25 mg/kg body weight and T₃ were fed with Vitamin E @ 150 mg/kg body weight for 35 days, respectively. Five broilers from each group (T₀, T₁, T₂, and T₃) were sacrificed at 15-day intervals to determine haematological and biochemical parameters. Results showed that in group T₁, body weight gain was minimal, whereas in group T₂ and T₃, the body weight gain in broilers was better. TLC, TEC, and Hb values were significantly reduced (P < 0.05) in T₁ group. Whereas in the rest groups reduction of TLC, TEC, and Hb was less than in arsenic-treated groups. SGPT, SGOT, and Serum creatinine values were increased in the As-treated group (T₁) than the control group (T₀) whereas in groups T₂ and T₃ the values were comparatively reduced. In conclusion, Selenium and vitamin E significantly affect body weight, and haematological and biochemical changes in the case of arsenicosis in the Broiler.