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September 10, 2025Asian Journal of Medical Research & Health Sciences (A-JMRHS)

Comprehensive NMR Spectral Analysis and Prediction of Selected Coumarin Derivatives Using 1H, 13C, 2D-COSY, HSQC, and HMBC Techniques

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Authors

JSJunapudi SunilYJYasodha Krishna JanapatiMCMallika Chikkala

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Overview

Analysis shows effective spectral prediction for coumarin derivatives using NMR techniques, indicating the utility of Spec2D in structural elucidation.

Key Points

  • The Spec2D system consistently ranked correct structures highest for all coumarin derivatives analyzed.
  • Input spectra included 1D (1H, 13C) and 2D (COSY, HSQC) data, demonstrating flexibility in handling various compounds.
  • Processing time per compound ranged from 30 seconds to 2 minutes, highlighting efficiency in spectral analysis.
  • Spec2D effectively utilized a COSY-driven knowledge base for reliable NMR-based structural elucidation.

Cite This Study

Sunil et al. (2025) studied this question.

synapsesocial.com/papers/68c1c32754b1d3bfb60f0f7chttps://doi.org/10.5455/ajmrhs.20250507
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