I2-DMSO mediated multi-component cascade cyclization to construct pyrazolo3,4-bpyrrolo3,4-dpyridine-6-one skeleton
Key Points
A one-pot synthesis effectively constructs a unique pyrazolo-pyrrolo-pyridine skeleton, enhancing efficiency.
Key substrates include aryl methyl ketones and 3-aminopyrazoles, demonstrating versatility in the synthesis process.
The methodology leverages multi-component cascade cyclization, showcasing innovative approaches in organic chemistry.
This synthesis method simplifies reactions, suggesting potential applications in drug development and material science.
Abstract
A one-pot synthesis of the pyrazolo3,4- b pyrrolo3,4- d pyridin-6-one skeleton has been developed using aryl methyl ketones, 3-aminopyrazoles, and enaminamides as substrates.