Resolving Loss of Response to Ustekinumab in Crohn’s Disease: POWER Through or Switch Treatment?

Journal Article Resolving Loss of Response to Ustekinumab in Crohn's Disease: POWER Through or Switch Treatment? Get access Daniele Noviello, MD , Daniele Noviello, MD Department of Pathophysiology and Transplantation, University of Milan, Milan, ItalyGastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy Corresponding author: Daniele Noviello, MD, Department of Pathophysiology and Transplantation, Via Francesco Sforza 35, 20122 Milan, Italy ([email protected]). https://orcid.org/0000-0002-3482-0109 Search for other works by this author on: Oxford Academic PubMed Google Scholar Raja Atreya, PhD , Raja Atreya, PhD Department of Medicine 1, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany https://orcid.org/0000-0002-8556-8433 Search for other works by this author on: Oxford Academic PubMed Google Scholar Nurulamin M Noor, PhD Nurulamin M Noor, PhD Department of Gastroenterology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United KingdomDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom Search for other works by this author on: Oxford Academic PubMed Google Scholar Inflammatory Bowel Diseases, izaf179, https://doi.org/10.1093/ibd/izaf179 Published: 20 August 2025 Article history Received: 17 July 2025 Editorial decision: 18 July 2025 Published: 20 August 2025