Stereotactic radiotherapy for lung cancer: Influence of prescription modality on clinical outcome

Stereotactic body radiotherapy, also referred to extreme hypofractionation, uses advanced delivery techniques to administer high radiation doses per fraction. Stereotactic body radiotherapy has led to a real revolution for the treatment in localized non-small cell lung cancer. Recognized as the standard treatment for inoperable early-stage non-small cell lung cancer, there is an increasing use of stereotactic body radiotherapy in complex situations related to patient or tumour characteristics. The aim of this review was to report the current evidence so far, and to assess specificities of this irradiation technique, especially in terms of dose prescription modalities.