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This is a Meta-Analysis study (also classified as: Observational).

September 10, 2025Neurology

Changes in Gray Matter Morphology and White Matter Microstructure Across the Adult Lifespan in People With Temporal Lobe Epilepsy

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Mega-analysis shows gray and white matter changes in temporal lobe epilepsy patients, indicating lifelong implications.

Patients with temporal lobe epilepsy exhibit significant gray and white matter atrophy throughout their adult lifespan.
Robust gray matter decline was observed across multiple brain regions, with significant differences from healthy controls.
Cross-sectional analysis revealed strong covariance between gray and white matter changes, particularly in older patients.
The findings highlight the need for early diagnosis and intervention to address alterations associated with drug-resistant epilepsy.

Chen et al. (2025) studied this question.

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September 10, 2025Neurology

View Full Paper

Ask AI

Bookmark

Authors

Mega-analysis shows gray and white matter changes in temporal lobe epilepsy patients, indicating lifelong implications.

Patients with temporal lobe epilepsy exhibit significant gray and white matter atrophy throughout their adult lifespan.
Robust gray matter decline was observed across multiple brain regions, with significant differences from healthy controls.
Cross-sectional analysis revealed strong covariance between gray and white matter changes, particularly in older patients.
The findings highlight the need for early diagnosis and intervention to address alterations associated with drug-resistant epilepsy.

Chen et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark