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August 23, 2025Clinical Otolaryngology

A Prospective Pilot Study of the Efficacy of Oral Propranolol in Reduction of the Frequency and Severity of Epistaxis in Hereditary Haemorrhagic Telangiectasia

Cameron Grigg Abigail Walker Anders Cervin Keith J. Girling Zhihong Liu J J Earnshaw

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Key Points

Propranolol significantly reduces the severity of epistaxis in patients with hereditary haemorrhagic telangiectasia, enhancing quality of life.
The study reported a noticeable decrease in epistaxis frequency, demonstrating the effectiveness of propranolol as a treatment option.
Using a prospective pilot study design, participants were treated with oral propranolol over a defined period to assess its impact.
These findings highlight the potential of propranolol for managing epistaxis, warranting further research in larger cohorts.

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Implication

Pilot study finds oral propranolol reduces epistaxis frequency in hereditary haemorrhagic telangiectasia, suggesting a potential treatment option.

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Cite This Study

Grigg et al. (2025) studied this question.

synapsesocial.com/papers/68c1d02354b1d3bfb60f6518 https://doi.org/10.1111/coa.70017

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1A prospective study of the efficacy of oral propranolol in reduction of the frequency and severity of epistaxis in Hereditary Haemorrhagic Telangiectasia2024
2Propranolol Reduces Epistaxis in Hereditary Hemorrhagic Telangiectasia: A Large Retrospective StudyObservational Study · 2026
3Epistaxis due to hereditary hemorrhagic telangiectasia: A case report and literature review.2025 · 2 citations
4Implementation and Outcomes of a Structured Epistaxis Protocol in Hereditary Hemorrhagic Telangiectasia: An Observational Cohort Study from a Multidisciplinary ClinicCohort Study · 2026
5Surgery or No Surgery? Exploring the Dilemma of Epistaxis Management in Patients with HHT2024 · 4 citations

Surgery or Not Surgery? Exploring the Dilemma of Epistaxis Management in Patients With HHT2024
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