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Evaluation of the Clinical and Haematological Response to Hydroxyurea Treatment in Patients with Sickle Cell Disease Attending the Haematology Clinic at Jitimai District Hospital

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Descriptive study evaluates hydroxyurea's clinical and haematological effects on SCD patients, suggesting significant benefits.

Hydroxyurea treatment significantly reduced painful crises in SCD patients, from a mean of 3.83 to 1.80.
Hospitalization rates dramatically decreased with treatment, dropping from 3.09 to 1.20, indicating improved patient stability.
The study found a considerable increase in haemoglobin levels from 5.49 g/dL to 7.82 g/dL, enhancing oxygen delivery.
Overall, hydroxyurea therapy shows strong efficacy in managing sickle cell disease and improving quality of life.

Okafor et al. (2025) studied this question.

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