Relapse of the ischemic heart disease clinical manifestations in patients with coronary artery bypass grafting

Introduction. Ischemic heart disease is a leading cause of mortality, while coronary artery bypass grafting is an effective treatment method for it, but does not eliminate the risk of the disease recurrence. In this regard, it is necessary to improve approaches to the monitoring of patients before and after coronary artery bypass grafting by studying marker indicators to prevent ischemic heart disease recurrences. Aim. To substantiate the need to study the determinants and prevent the relapse of ischemic heart disease clinical manifestations in patients after coronary artery bypass grafting. Materials and Methods. Analysis of research literature describing the concept and clinical manifestations of ischemic heart disease and its treatment methods, as well as of the essence of coronary artery bypass grafting in the treatment of ischemic heart disease. Results and Discussion. Analysis of factors influencing the relapse of the ischemic heart disease clinical manifestations after coronary artery bypass grafting revealed key determinants, including insufficient control of modifiable risk factors, low patients’ awareness, and their non-adherence to therapy. Additional influences include psychosocial stress, decreased quality of life, as well as an increase in non-modifiable risk factors in the absence of an adequate preventive strategy. Conclusions. A comprehensive approach is needed to address the problem of the relapse of the ischemic heart disease clinical manifestations in patients after coronary artery bypass grafting. This involves parallel activities aimed at identifying the determinants of its relapse, initial and dynamic clinical, biochemical, and instrumental indicators thereof, controlling risk factors, as well as in the field of increasing the awareness of patients with ischemic heart disease who have undergone coronary artery bypass grafting, regarding their further organization of life and health preservation.