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September 10, 2025Marine DrugsOpen Access

Selective Utilization of Polyguluronate by the Human Gut Bacteroides Species

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Authors

NLNuo LiuMLMing LiXYXiao Yuan

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Overview

Observational analysis of PG utilization in 17 Bacteroides species, highlighting distinct metabolic profiles.

Key Points

  • Each Bacteroides species displays unique capabilities for polyguluronate utilization, emphasizing their metabolic diversity.
  • Mass spectrometry detected oligosaccharides resulting from PG degradation by Bacteroides xylanisolvens, the highest consumer of PG.
  • Genomic analysis revealed that Bacteroides xylanisolvens harbors a diverse array of carbohydrate-active enzymes, critical for PG breakdown.
  • This research indicates potential pathways for developing carbohydrate-based drugs from marine resources, based on Bacteroides metabolism.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68c1d98f54b1d3bfb60fb656https://doi.org/10.3390/md23090348
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