Case-control study identifies salivary biomarkers MDA, IL-6, and LDH as diagnostic tools for oral precancer.
Key Points
Salivary levels of malondialdehyde, interleukin-6, and lactate dehydrogenase are significantly elevated in patients with oral precancerous lesions, suggesting a potential for early detection.
Elevated biomarkers MDA, IL-6, and LDH in patients revealed enhanced diagnostic performance, with IL-6 displaying the highest accuracy in distinguishing lesion presence.
This case-control study analyzed salivary samples from patients at the Oncology Center, demonstrating a clear connection between elevated biomarker levels and oral precancerous conditions.
The findings support the potential incorporation of these salivary assays as non-invasive screening tools in routine clinical practice to reduce oral cancer progression.
Cite This Study
Ghufran Salman Abd Alhussain (2025) studied this question.