This review examines molecular mechanisms of chemotherapy-induced cognitive impairments in survivors, highlighting transcriptomic analyses and neuroinflammation.
Key Points
Chemotherapy-induced cognitive impairments significantly affect cancer survivors' quality of life and memory.
Key mechanisms like neuroinflammation and oxidative stress play vital roles in chemobrain development.
Advanced transcriptomic methodologies reveal alterations in gene expression linked to cognitive dysfunction.
Integrating transcriptomic insights with clinical findings aims to enhance personalized interventions for improved cognitive health.