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Case analysis demonstrates proper diagnosis using immunohistochemistry in oncology, highlighting potential misapplications.
Arrival of immunohistochemistry in the domain of Oncology has revolutionised our approach towards diagnosis as well as in therapeutic decision making. Here, the authors will like to discuss two interesting cases (53-year-old female and 26-year-old male) encountered in the Institution where immunohistochemistry came out to be instrumental in clinching the proper diagnosis. The second case also highlights how misleading it can be, if not applied in appropriate clinical context and without being fully coherent with immunophenotypical spectrum of commonly encountered tumours.
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Hota et al. (2025) studied this question.
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