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September 10, 2025BMC CancerOpen Access

Comparison of short- and long-term outcomes among total laparoscopic, laparoscopic-assisted, and open total gastrectomies for advanced gastric cancer patients after neoadjuvant chemotherapy: a multicenter retrospective cohort study

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Authors

XGXiaopeng GaoZLZiyang LiJYJia Yuan

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Overview

Retrospective cohort study compares outcomes of laparoscopic, laparoscopic-assisted, and open surgery in gastric cancer patients, indicating similar results overall.

Key Points

  • The totally laparoscopic approach resulted in faster postoperative recovery, but longer operation times.
  • Operation time and blood loss varied between surgical approaches, yet overall outcomes showed no significant differences.
  • This study involved 289 patients with gastric cancer, conducted across five centers to evaluate surgical outcomes.
  • Short- and long-term outcomes remained similar among the total laparoscopic, laparoscopic-assisted, and open groups.

Cite This Study

Gao et al. (2025) studied this question.

synapsesocial.com/papers/68c1dd9254b1d3bfb60fbd7fhttps://doi.org/10.1186/s12885-025-14765-x
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Classification of Surgical Complications2004 · 31,598 citations
  2. 2Totally laparoscopic versus laparoscopy-assisted distal gastrectomy: the KLASS-07: a randomized controlled trial2024 · 19 citations
  3. 3Laparoscopic and open gastrectomy for locally advanced gastric cancer: a retrospective analysis in Colombia2023 · 8 citations
  4. 4Effect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric Cancer2019 · 725 citations