Glycemic discordance: How to match glycemia with glycemic indices?

Management of diabetes requires regular monitoring of glycemic parameters. In certain occasions, the actual glycemic status of individuals might not match with measured indices. In such cases, careful consideration of several factors that influence the variation needs to be taken into account, and a proper explanation of variability has to be documented in order to reduce the burden of misdiagnosis and inappropriate treatment. Here, the two cases exemplify the need for simple scientific observation and interpretation while diagnosing and managing diabetes.