High-Frequency Ultrasound in Eccrine Poroma Diagnosis: A Retrospective Analysis of Distinctive Imaging Characteristics.

This study aims to delineate the ultrasonographic characteristics of eccrine poroma (EP), using high-frequency ultrasound (HFUS) to facilitate non-invasive diagnosis and differentiation from other cutaneous lesions. Retrospective analysis of 15 patients with histopathologically confirmed EP who underwent preoperative HFUS examination (5-18 MHz) between January 2017 and May 2025. Systematic evaluation included morphological assessment, echogenicity characterization, compositional analysis, and vascular assessment using standardized Doppler grading. This study enrolled 15 patients (mean age 56.60 ± 16.90 years) with solitary lesions ranging from 5.5 to 30.2 mm in diameter. Morphologically, 66.7% presented elliptical configurations, with 86.7% demonstrating well-defined margins. Ultrasonographically, 86.7% exhibited heterogeneous hypoechoic patterns with mixed solid-cystic architecture (cystic component <50%), while smaller lesions (13.3%) showed homogeneous hypoechoic characteristics. All cases demonstrated detectable vascular flow: Grade 3 vascularity in 60.0% and Grade 2 in 40.0%. EP demonstrates consistent ultrasonographic features including heterogeneous hypoechoic architecture, well-defined margins, predominantly solid-cystic composition, and robust vascular perfusion. These findings provide the first comprehensive characterization of EP's imaging features, establishing a foundation for integrating HFUS into diagnostic algorithms and enhancing pre-operative assessment accuracy.