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September 14, 20250 citations

Liraglutide Reduces Fatty Infiltration and Improves Function After Rotator Cuff Repair in Rats

GLP-1RA Reduces Supraspinatus Fatty Infiltration and Promotes Functional Recovery in a Rat Model of Rotator Cuff Repair.

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Authors

JYJong Pil YoonSPSung-Jin ParkDKDong-Hyun Kim

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Overview

Controlled study shows liraglutide reduces fatty infiltration and enhances shoulder function in rats, indicating its potential therapeutic role.

Key Points

  • Liraglutide significantly reduced fatty infiltration in the supraspinatus muscle after rotator cuff surgery, improving recovery.
  • Rats treated with liraglutide exhibited improved shoulder function and muscle strength through internal and external rotation assessments.
  • No differences were found in muscle atrophy or fat browning gene expression despite liraglutide's positive functional outcomes.
  • This treatment demonstrates liraglutide’s potential as a strategy for postoperative care in obese patients with rotator cuff injuries.

Cite This Study

Yoon et al. (2025) studied this question.

synapsesocial.com/papers/68c6df6edb42462b79dccc3bhttps://doi.org/10.1177/03635465251369517
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