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September 16, 2025

Heterogeneous Evolution Among SARS-CoV-2 Genes and Variants of Concern.

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Authors

LGLuis Daniel González-VázquezPIPaula Iglesias-RivasDFDavid Ferreiro

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Overview

Analysis reveals fluctuating genetic diversity in SARS-CoV-2 variants, indicating complex molecular evolution dynamics.

Key Points

  • A low overall genetic diversity was observed in SARS-CoV-2, with significant fluctuations across genomic regions and time.
  • The rate of molecular evolution was estimated to be about 10^-3 substitutions per site per year, varying among regions.
  • Analysis involved thousands of SARS-CoV-2 genomes, assessing evolution rates and selective pressures across coding regions.
  • Ongoing monitoring of SARS-CoV-2 evolution is essential due to its heterogeneous molecular adaptation and evolutionary patterns.

Cite This Study

González-Vázquez et al. (2025) studied this question.

synapsesocial.com/papers/68c93fe601120bef803badfbhttps://doi.org/10.1002/jmv.70604
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