Observational analysis found increased viraemia and two encephalitis cases in CAR T-cell recipients, suggesting further investigation is warranted.
HHV-6 reactivation in CAR T-cell recipients is reported to be rare. Our patient cohort (n=119) experienced a seven-fold higher incidence of viraemia than a previous study and 2 encephalitis cases. Further studies are needed to determine risk factors for infection.
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Isaac et al. (2025) studied this question.
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