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Expert Panel assesses safety of carica papaya ingredients in cosmetic formulations, suggesting good manufacturing practices.
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 5 Carica papaya (papaya)-derived ingredients as used in cosmetic formulations. These ingredients are mostly reported to function in cosmetics as skin-conditioning agents. Industry should continue to use good manufacturing practices to limit impurities that could be present in these botanical ingredients. The Panel considered all the information, and concluded that Carica Papaya (Papaya) Fruit, Carica Papaya (Papaya) Fruit Extract, Carica Papaya (Papaya) Fruit Juice, and Carica Papaya (Papaya) Fruit Water are safe in cosmetics in the present practices of use and concentration described in this safety assessment, and that the available data are insufficient to make a determination of safety for Carica Papaya (Papaya) Leaf Extract under the intended conditions of use in cosmetic formulations.
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Ferguson et al. (2025) studied this question.
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