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This review highlights the high mortality rate of Boerhaave’s syndrome and the role of the Pittsburgh score in guiding management strategies.
Boerhaave’s syndrome (BS), or spontaneous esophageal perforation, is a rare and life-threatening condition. Despite advancements in medical and surgical management, BS carries a high mortality rate, up to 50%, and presents significant diagnostic and therapeutic challenges. Management options include both surgical and nonoperative approaches, with the Pittsburgh score providing a useful tool for predicting outcomes and guiding treatment. Complications such as mediastinitis and sepsis are common. This review explores the demographics, risk factors, clinical presentation, diagnostic modalities, and management strategies for BS. Furthermore, it stresses the importance of early diagnosis and individualized treatment to improve the outcomes in patients with BS.
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Sherrin et al. (2025) studied this question.
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