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September 12, 2025Drugs & Aging10 citationsOpen Access

Medication Non-adherence in Older Adults: Underlying Factors, Potential Interventions and Outcomes

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ERElstin Anbu RajRVR VilakkathalaJGJohnson George

Key Points

  • Medication non-adherence in older adults often results in poor health outcomes and increased healthcare costs.
  • Key factors impacting adherence include socio-demographics, health conditions, and healthcare providers' roles.
  • Educational and behavioral interventions can optimize medication use and improve patient safety.
  • Engaging patients and families in the treatment process may enhance self-management and adherence.

Abstract

Polypharmacy is very common among older adults and is associated with poor health outcomes. This scoping review aimed to understand the underlying factors for poor medication taking by older patients and potential solutions to mitigate these risks. The ability to take medications and adherence are affected by various factors related to patients, treatments, health conditions and socio-demographics, healthcare providers and the healthcare systems. Educational and behavioural interventions are used alone or in combination for the optimisation medication use. Medication review and deprescribing, including regimen simplification, by trained practitioners has the potential to enhance patient safety and reduce healthcare costs. Engaging the patient and family may bring about additional benefits. Various technology-based interventions to promote self-efficacy are evolving and are used to support consumer self-management.

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Cite This Study

Raj et al. (2025) studied this question.

synapsesocial.com/papers/68d44b3031b076d99fa548abhttps://doi.org/10.1007/s40266-025-01249-7
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Medication adherence in older adults with chronic diseases: a scoping review of barriers, facilitators, and effective interventions2026
  2. 2Promoting Medication Adherence in the Elderly: Factors and Insights From a Cross‐Sectional Study2026 · 2 citations
  3. 3Improving Medication Outcomes in Older People1999 · 15 citations
  4. 4Drug adherence and symptom management in older people2018 · 2 citations
  5. 5Multilevel Interventions to Improve Medication Adherence in Older Adults: A Systematic Review and Meta-Analysis of Cognitive, Digital, Behavioral, and Socioeconomic Strategies (2015–2025)2026 · 4 citations