The role of pharmacies in implementing modern protocols for the pharmacotherapy of type 2 diabetes mellitus

The incidence of diabetes in different countries ranges from 1.5 to 10% and only about 50% of patients with type 2 diabetes achieve glycemic control. Therefore, studying factors that contribute to improving disease control and preventing complications is relevant. The aim is to study the capabilities of a pharmacy in implementing modern guidelines for pharmacotherapy of type 2 diabetes based on an analysis of the assortment and sales of the hypoglycemic drugs over a 3-month period. Materials and methods: assortment of hypoglycemic drugs in a pharmacy, sales report of various pharmacological groups of hypoglycemic drugs and fixed-dose combination drug. Analytical and statistical methods were used in the research. Results. Analysis of the assortment of hypoglycemic drugs in the pharmacy showed the presence of five out of six pharmacological classes recommended by modern guidelines: Biguanides, Inhibitors of sodium-dependent glucose cotransporter type 2, Antagonists of glucagon-like peptide type 1 receptors, Dipeptidyl peptidase 4 inhibitors and Sulfonylureas. Thiazolidinediones are absent in the pharmacy. This range of hypohlygemic drugs corresponds the international guidelines and the Unified Ukrainian Clinical Protocol for Medical Care for Type 2 Diabetes. Analysis of sales of hypoglycemic drugs in the pharmacy showed that the leading positions in sales are occupied by Biguanides and Sulfonylureas. Combined hypoglycemic drugs in the pharmacy are represented by combinations of Biguanides with Sulfonylureas, with Dipeptidyl peptidase 4 inhibitors and Inhibitors of sodium-dependent glucose cotransporter type 2. But sales of combined diabetes-lowering drugs in pharmacies account for only 28.34%, with 40.3% of them being sales of the combination of Metformin and Glibenclamide. Conclusions. The results of the research showed that modern guidelines for pharmacotherapy of type 2 diabetes are partially implemented in pharmacies, but at the same time, patients' access to drugs that allow for effective control of glycemia is ensured. The key negative trends are the low percentage of sales of drugs for the prevention of complications of diabetes and fixed-dose combination drug. To improve the practical implementation of guidelines, it is necessary to pay more attention to the study of dynamic changes in international guidelines and the Ukrainian Clinical Protocol For Medical Care For Type 2 Diabetes during the continuous professional development of pharmacy specialists.