This research demonstrates that alginate film significantly improves wound healing in patients following thoracoscopic surgery, suggesting enhanced postoperative recovery strategies.
The healing process of postoperative wounds is a dynamic and complex. Thoracoscopic surgery, as a new minimally invasive technique in thoracic surgery, is of great significance in exploring the postoperative recovery quality of patients undergoing this surgery. Therefore, this study uses micro controlled flow spinning technology to prepare a calcium alginate fiber coating (CaAFC) film using materials such as sodium alginate (SA). Combined with thermal insulation nursing during the recovery period, the effect of this film was explored in patients undergoing thoracoscopic general anesthesia surgery (TGAS), and it was applied in animal experiments simulating TGAS. The results showed that the permeability of the CaAFC was 93 g/m2·24 h, the porosity was 73 %, and the water absorption rate was 21.5 g/g, demonstrating good breathability and water absorption. The relative growth rate (RGR) of HaCaT cells under CaAFC was 1.52, and the stress fiber staining intensity (SFSI) was 1.31, both of which were higher than the other two dressings. These findings indicated that the material was non-toxic to cells and could significantly improve cell activity. The wound healing rate of mice treated with CaAFC on the 15th day after surgery was 96.3 %, which was significantly higher than that of mice treated with traditional alginate medical dressings (TAMD) and medical gauze (MG). These results indicated that CaAFC could promote wound healing. The above results indicate that the CaAFC has good breathability, water absorption, and antibacterial properties. Moreover, it can significantly promote wound healing, increase cell activity, reduce postoperative infection risk, and provide support for improving postoperative care for patients undergoing thoracoscopy surgery in clinical practice.
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Lu et al. (2025) studied this question.
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