PulseTrendingJournal ClubResearchersJournalsExplore
Instagram
HomeTrendingJournal ClubExplore
Synapse
⌘+K
Synapse
September 14, 2025Neurological SciencesOpen Access

Advancing glioblastoma therapy with surface-modified nanoparticles

View Full Paper
Ask AI
Bookmark
Share

Authors

GRGiorgia De RosaMZMarco ZeppieriCGCaterina Gagliano

Discussion

Loading...

Member takes

Overview

Narrative review highlights targeted drug delivery and efficacy improvements in glioblastoma using nanoparticles.

Key Points

  • Surface-modified nanoparticles enhance drug delivery effectiveness, reducing systemic toxicity and increasing treatment precision.
  • Key methods include receptor-mediated targeting, leading to improved medication efficacy and penetration in resistant glioblastoma cases.
  • In vivo studies demonstrate the translational potential of surface-modified nanoparticles, paving the way for clinical applications.
  • Challenges remain in managing nanoparticle toxicity and ensuring their scalability for widespread therapeutic use.

Cite This Study

Rosa et al. (2025) studied this question.

synapsesocial.com/papers/68d44f7b31b076d99fa56cd4https://doi.org/10.1007/s10072-025-08457-4
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Targeted delivery of nanomedicines to glioblastoma: Overcoming the clinical barrier2024 · 19 citations
  2. 2The “Trojan Horse” Approach to Tumor Immunotherapy: Targeting the Tumor Microenvironment2014 · 52 citations
  3. 3Magnetic fluid hyperthermia (MFH)reduces prostate cancer growth in the orthotopic Dunning R3327 rat model2005 · 200 citations
  4. 4A Critical Overview of Targeted Therapies for Glioblastoma2018 · 249 citations
  5. 5Theranostic AGuIX nanoparticles as radiosensitizer: A phase I, dose-escalation study in patients with multiple brain metastases (NANO-RAD trial)2021 · 163 citations