Table S5 from Transcriptome Analysis of Matched Cohorts of Long- and Short-term Survivors in Advanced High-grade Serous Tubo-ovarian Cancer

Q: What type of study is this?

This is a Quantitative Study study.

Sofya Marchenko; Niklas Goernitz; Wiebke A. Zoern; Maria Joosten; Inga Hoffmann; Jalid Sehouli; Gerald Niedobitek; Carsten Denkert; Bruno V. Sinn; Svenja Kolb; José Carbonell‐Caballero; Alfonso Valencia; Mihnea P. Dragomir; Wolfgang Schmitt; David Horst; Elena Ioana Braicu; Christine Sers; Jonathan Pohl; Eliane T. Taube

doi:10.1158/1078-0432.30125571

Key Points

Long-term survivors of tubo-ovarian cancer show distinct hrd-scores compared to short-term survivors, indicating potential genomic differences.
Key findings reveal variations in brca1 and brca2 statuses, vital genetic markers in cancer prognosis.
This cohort analysis utilizes detailed transcriptome data from the Charité cohort, providing insights into patient survival outcomes.
Understanding the genetic landscape may refine treatment strategies and improve patient prognostication in advanced cancer cases.

Implication

Analysis demonstrates differences in brca1, brca2, and hrd-scores between long- and short-term survivors in tubo-ovarian cancer cohorts, suggesting potential genetic implications.

Abstract

Table S5 depicts the BRCA1/2, KRAS Status and HRD-Scores in LTS and STS in the Charité Cohort.

Discussion

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Cite This Study

Marchenko et al. (2025) studied this question.

synapsesocial.com/papers/68d4538731b076d99fa5891f https://doi.org/10.1158/1078-0432.30125571

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Table S5 from Transcriptome Analysis of Matched Cohorts of Long- and Short-term Survivors in Advanced High-grade Serous Tubo-ovarian Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

Table S5 from Transcriptome Analysis of Matched Cohorts of Long- and Short-term Survivors in Advanced High-grade Serous Tubo-ovarian Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

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