Investigation reveals how molecular structure influences sweetness in chalcones, suggesting better sweeteners. This work emphasizes 3D-QSAR models for natural sweeteners' development.
Natural plant-derived chalcones exhibit sweetening properties and bioactive health benefits, making them promising natural sweeteners. However, their unsatisfying sweetness intensity restricts their applications in food industry. To clarify the structure-sweetness...
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Chen et al. (2025) studied this question.
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